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Symbol
Name
ID 		Cd14
CD14 antigen
MGI:88318
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Eosinophilia
Increased T cell count
Leukopenia
Sinusitis
Chronic sinusitis
Keratoconjunctivitis sicca
Abnormal lymph node morphology
Lymphadenopathy
Hepatosplenomegaly
Pancreatitis
Uveitis
Nephritis
Erythema nodosum
Maculopapular exanthema
Recurrent pneumonia
Asthma
Nontuberculous mycobacterial pulmonary infection
Recurrent Burkholderia cepacia infections
Recurrent Haemophilus influenzae infections
Recurrent Staphylococcus aureus infections
Recurrent Aspergillus infections
Recurrent respiratory infections
Recurrent bronchopulmonary infections
Recurrent lower respiratory tract infections
Disease(s) Associated with CD14
asthma
cystic fibrosis
IgA glomerulonephritis
sarcoidosis

Mouse Phenotypes
abnormal neutrophil physiology
abnormal macrophage physiology
decreased circulating interleukin-6 level
decreased circulating tumor necrosis factor level
abnormal cytokine level
abnormal interleukin level
abnormal tumor necrosis factor level
abnormal cytokine secretion
abnormal interferon secretion
decreased interleukin-6 secretion
decreased tumor necrosis factor secretion
decreased susceptibility to endotoxin shock
decreased susceptibility to bacterial infection
decreased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to Riboviria infection
Availability Mouse Genotype
Cd14hdl/Cd14hdl
Cd14tm1Frm/Cd14tm1Frm
Cd14tm1Smg/Cd14tm1Smg
Cd14tm1Frm/Cd14+
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory